Reproductive performance of patients undergoing intracytoplasmic sperm injection with 100% implantation rate

Purpose: To characterize the differences between two matched groups of pati ents treated by ICSI: those pregnant after all embryos transferred implante d (100% implantation rate) compared with nonpregnant patients. Methods: Twenty-one patients in whom one transferred embryo achieved a sing leton pregnancy (group A) and 21 pregnant patients to whom two or three emb ryos were transferred and achieved 11 twin and 10 triplet pregnancies (grou p B) compared with matched nonpregnant patients (group C and D, respectivel y). Results: The singleton pregnant patients were significantly older than the twin and triplet pregnancy patients. Although a similar number of human men opausal gonadotropin ampules were used in the singleton compared with the t wins and triplets a significantly lower number of oocytes and embryos were achieved at lower levels of estradiol on the human chorionic gonadotropin d ay in the former than in the latter respectively. No difference was found b etween the pregnant women and their nonpregnant controls in any of the ment ioned parameters. Good embryo morphology was found in 86% of the embryos in group A compared with 62% in group C (P = 0.08) and 92% in group B compare d with 66% in group D (P < 0.002). Conclusions: The only parameter in which pregnant patients with 100% implan tation rate differ from their nonpregnant controls was embryo quality.