The recent National Research Council report, future Biotechnology Research
on the International Space Station, evaluates NASA's plans for research in
cell science and protein crystal growth to be conducted on the Internationa
l Space Station. This report concludes that the NASA biotechnology programs
have the potential to significantly impact relevant scientific fields and
to increase understanding and insight into fundamental biological issues. I
n order to realize the potential impacts, NASA must focus its research prog
rams by selecting specific questions related to gravitational forces' role
in cell behavior and by using the microgravity environment as a tool to det
ermine the structure of macromolecules with important biological implicatio
ns. Given the time and volume constraints associated With space-based exper
iments, instrumentation to be used on the space station must be designed to
maximize the productivity of researchers, and NASA's recruitment of invest
igators and support for space station experiments should aim to encourage a
nd facilitate cutting-edge research. Published 2000 Wiley-Liss, Inc.dagger