Determination of optical purity of phosphonic acid analogues of aromatic amino acids by capillary electrophoresis with alpha-cyclodextrin

Authors
Dzygiel, P Rudzinska, E Wieczorek, P Kafarski, P
Citation
P. Dzygiel et al., Determination of optical purity of phosphonic acid analogues of aromatic amino acids by capillary electrophoresis with alpha-cyclodextrin, J CHROMAT A, 895(1-2), 2000, pp. 301-307
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
JOURNAL OF CHROMATOGRAPHY A → ACNP
Volume
895
Issue
1-2
Year of publication
2000
Pages
301 - 307
Database
ISI
SICI code
Abstract
A simple and efficient method for the determination of enantiomeric purity of structurally diverse phosphonic and phosphinic acid analogues of phenyla lanine and phenylglycine using capillary electrophoresis is presented. Thes e preliminary studies indicated that the enantiomer separation is strongly dependent on the structure of the aminophosphonic acid. (C) 2000 Elsevier S cience B.V. All rights reserved.