Novel visualization method for biological sequence similarity reports

Citation
Eh. Chi et al., Novel visualization method for biological sequence similarity reports, J ELECTR IM, 9(4), 2000, pp. 394-403
Citations number
13
Categorie Soggetti
Optics & Acoustics
Journal title
JOURNAL OF ELECTRONIC IMAGING
ISSN journal
10179909 → ACNP
Volume
9
Issue
4
Year of publication
2000
Pages
394 - 403
Database
ISI
SICI code
1017-9909(200010)9:4<394:NVMFBS>2.0.ZU;2-R
Abstract
Previously, we presented a system called Alignment Viewer that uses informa tion visualization techniques to visualize similarities between a single DN A sequence and a large database of other sequences [Chi et al., IEEE Visual ization '95 pp. 44-51, IEEE CS (1995); Chi et al.. IEEE Visualization '96, pp. 133-140 and 477, IEEE CS (1996)]. In this paper, we extend, summarize, and describe the system using several interesting case studies, We present our comb glyph technique for visualizing alignments between sequences. In t his paper, we also extend the original system by incorporating computationa l steering, and the visualization of differences between data sets. The cas e studies and the new extended system present our approach of extracting si gnificant relationships in the biological data set. (C) 2000 SPIE and IS&T. [S1017-9909(00)01204-6].