Computational modelling of blood flow through curved stenosed arteries

A computational model of three-dimensional blood flow in curved arteries wi th elliptic stenosis was developed. Two groups of models, (a) different ang les of curvature and (b) degrees of stenosis, have been studied under typic al conditions for stenosed coronary artery. Useful information on the haemo dynamics has been obtained. Results of pressure drop show that the presence of the curvature augments the increased flow resistance due to stenotic le sions. The study also demonstrates the significant presence of secondary fl ow in a curved artery. In addition, the results have shown that the seconda ry flow in a curved artery brings about elevated shear stress on the vessel wall. These results indicated that both curvature and stenosis should be c onsidered together by cardiologists to assess or quantify the severity of t he stenosis. This study employed a powerful computer-aided design (CAD) pac kage to construct the model and a commercial computational fluid dynamics ( CFD) code for the analysis of blood flow in stenosed arteries. The long-ter m application of this form of research promises to be an effective tool for gaining insights into the pathology of arterial diseases.