The effect of anticonvulsant drugs on blood levels of methotrexate

Authors
Riva, M Landonio, G Defanti, CA Siena, S
Citation
M. Riva et al., The effect of anticonvulsant drugs on blood levels of methotrexate, J NEURO-ONC, 48(3), 2000, pp. 249-250
Citations number
5
Categorie Soggetti
Oncology
Journal title
JOURNAL OF NEURO-ONCOLOGY
ISSN journal
0167594X → ACNP
Volume
48
Issue
3
Year of publication
2000
Pages
249 - 250
Database
ISI
SICI code
0167-594X(200007)48:3<249:TEOADO>2.0.ZU;2-K
Abstract
The reduced bioavailability of chemotherapeutic agents is one of the reason s that explains the limited efficacy of adjuvant chemotherapy in high grade glioma patients. We report how even the results of high dose sequential ch emotherapy can be influenced by antiepileptic drugs.