Image fusion using an integrated, dual-head coincidence camera with x-ray tube-based attenuation maps

The purpose of this study was to characterize a dual-head gamma camera capa ble of FDG imaging using coincidence detection and equipped with an integra ted x-ray transmission system for attenuation correction, anatomic mapping, and image fusion. Methods: Radiation dose (425 mrads skin dose) and tissue contrast (0.7% deviation from expected values) were assessed for the x-ray system. Registration of transmission and emission scans was validated usin g a hot sphere phantom and was verified in selected patient studies. Result s: Fusion of anatomic maps and FDG images allowed precise anatomic localiza tion of lesions identified using dual-head coincidence imaging. Conclusion: The combined approach of x-ray attenuation, anatomic mapping, and image fu sion with scintigraphic studies provides a new diagnostic tool for nuclear medicine and fertile ground for future research.