MERKEL CELL-CARCINOMA OF THE SKIN - TREATMENT OF PRIMARY, RECURRENT AND METASTATIC DISEASE - REVIEW OF CLINICAL CASES

Authors
QUEIROLO P GIPPONI M PERESSINI A RAPOSIO E VECCHIO S GUENZI M SERTOLI MR SANTI P CAFIERO F
Citation
P. Queirolo et al., MERKEL CELL-CARCINOMA OF THE SKIN - TREATMENT OF PRIMARY, RECURRENT AND METASTATIC DISEASE - REVIEW OF CLINICAL CASES, Anticancer research, 17(3C), 1997, pp. 2339-2342
Citations number
22
Categorie Soggetti
Oncology
Journal title
Anticancer research → ACNP
ISSN journal
02507005
Volume
17
Issue
3C
Year of publication
1997
Pages
2339 - 2342
Database
ISI
SICI code
0250-7005(1997)17:3C<2339:MCOTS->2.0.ZU;2-V
Abstract
The clinical features of 10 cases of primary neuroendocrine carcinoma of the skin (Merkel cell tumor) are reported. This cancer arises in th e dermis and subcutaneous tissues of elderly individuals. Natural hist ory is characterized by local recurrences (30%), regional lymphnode me tastases (65%) and distant metastases (40%). Surgery is elective treat ment, chemotherapy and radiotherapy resulted only to short-term pallia tive response.