QSAR studies on antihypertensive thiadiazoles

Authors
Agrawal, VK Bano, S Khadikar, PV
Citation
Vk. Agrawal et al., QSAR studies on antihypertensive thiadiazoles, NATL ACAD S, 23(1-2), 2000, pp. 21-27
Citations number
8
Categorie Soggetti
Multidisciplinary
Journal title
NATIONAL ACADEMY SCIENCE LETTERS-INDIA
ISSN journal
0250541X → ACNP
Volume
23
Issue
1-2
Year of publication
2000
Pages
21 - 27
Database
ISI
SICI code
0250-541X(200001/02)23:1-2<21:QSOAT>2.0.ZU;2-0
Abstract
Main arterial blood pressure (MABP) for a series of 2-aryl-5-guanidino-1,3, 4-thiadiazoles was modeled using quantum chemical descriptors (E-H, E-L and E-T) Regression analysis has shown that MABP is best modeled in multiparam etric correlations upon the introduction of dummy parameters.