Citation
T. Meier et Ma. Ruegg, The role of dystroglycan and its ligands in physiology and disease, NEWS PHYSL, 15, 2000, pp. 255-259
Citations number
17
Categorie Soggetti
Physiology
Journal title
NEWS IN PHYSIOLOGICAL SCIENCES
ISSN journal
08861714
→ ACNP
Volume
15
Year of publication
2000
Pages
255 - 259
Database
ISI
SICI code
0886-1714(200010)15:<255:TRODAI>2.0.ZU;2-4
Abstract
Dystroglycan contributes to the formation of basement membrane during embry
onic development and enforces cell membrane integrity by bridging cytoskele
ton and components of the extracellular matrix. In several forms of muscle
disease, dystroglycan is reduced in abundance. Moreover, human viral and ba
cterial pathogens use dystroglycan as their cellular entry point.