Efficacy of inhalation form of furosemide to prevent postsurgical relapsesof rhinosinusal polyposis

The aim of the work is to demonstrate the efficacy of furosemide to prevent relapses of rhinosinusal polyps after surgical treatment. Two groups of pe ople with rhinosinusal polyposis were enrolled: the study group consisted o f 64 patients and the control group of 40 subjects. After surgical treatmen t, the study group started the therapy with topical furosemide; the control group had no treatment administered after the operation. Six years after t he operation only 4 cases of relapse were noticed in the study group (10%), while there were 12 relapses, 4 slight (6.4%) and 8 severe (20%), in the c ontrol group. In conclusion, furosemide could represent a valid therapeutic aid in the prevention of nasosinusal polyps. Copyright (C) 2000 S. Karger AG, Basel.