In this Rapid Communication we present results from the analysis of the iso
topic yields of fragments emitted in two selected reactions: the decay of t
he quasiprojectile in Au+Au peripheral collisions at 35 MeV/nucleon, and th
e disassembly of the unique source formed in Xe+Cu central reactions at 30
MeV/nucleon. We find that the relative yields of neutron-rich isotopes incr
ease with the excitation energy of the emitting sources. In the framework o
f a statistical multifragmentation model which reproduces fairly well the e
xperimental observables, such behavior can be explained with the increase o
f the N/Z ratio of the hot primary fragments. This corresponds to the stati
stical evolution of the fragmentation mechanism as a function of the excita
tion energy, from the decay into few small fragments with a heavy residue t
o complete multifragmentation.