Convenient preparation of 2-substituted cyclobutanones from esters of 2-alkoxyalkanoic acids

Authors
Shevchuk, TA Kulinkovich, OG
Citation
Ta. Shevchuk et Og. Kulinkovich, Convenient preparation of 2-substituted cyclobutanones from esters of 2-alkoxyalkanoic acids, RUSS J ORG, 36(4), 2000, pp. 491-495
Citations number
28
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
10704280 → ACNP
Volume
36
Issue
4
Year of publication
2000
Pages
491 - 495
Database
ISI
SICI code
1070-4280(200004)36:4<491:CPO2CF>2.0.ZU;2-2
Abstract
Esters of 2-alkoxyalkanoic acids react with ethylmagnesium bromide in the p resence of titanium(IV) isopropoxide in catalytic amounts to afford 1-(l-al koxy)alkyl-I-cyclopropanols which under acidic catalysis cleanly rearrange into 2-substituted cyclobutanones.