Septic arthritis is a rarely reported manifestation of disease due to Strep
tococcus pneumoniae. We have reviewed our recent experience of this diseaes
e in 14 adult patients. Common features in patients with S, pneumoniae sept
ic arthritis included advanced age (median = 63 y), pre-existing joint dise
ase (6/14), large joint disease (14/14), polyarthritis (6/14), and associat
ed meningitis, pneumonia or both (6/14), Two patients with septic arthritis
and meningitis, and another with Down's syndrome and sleep apnoea, died du
ring treatment. In the remaining 11 patients, treatment for at least 19 d,
predominantly with intravenous benzyl penicillin, plus joint lavage, result
ed in cure.