Diversity and dynamics of dendritic signaling

Citation
M. Hausser et al., Diversity and dynamics of dendritic signaling, SCIENCE, 290(5492), 2000, pp. 739-744
Citations number
129
Categorie Soggetti
Multidisciplinary,Multidisciplinary,Multidisciplinary
Journal title
SCIENCE
ISSN journal
00368075 → ACNP
Volume
290
Issue
5492
Year of publication
2000
Pages
739 - 744
Database
ISI
SICI code
0036-8075(20001027)290:5492<739:DADODS>2.0.ZU;2-N
Abstract
Communication between neurons in the brain occurs primarily through synapse s made onto elaborate treelike structures called dendrites. New electrical and optical recording techniques have Led to tremendous advances in our und erstanding of how dendrites contribute to neuronal computation in the mamma lian brain. The varied morphology and electrical and chemical properties of dendrites enable a spectrum of local and Long-range signaling, defining th e input-output relationship of neurons and the rules for induction of synap tic plasticity. In this way, diversity in dendritic signaling allows indivi dual neurons to carry out specialized functions within their respective net works.