NEW INSIGHTS INTO THE CONTROL OF CELL-GROWTH - THE ROLE OF THE AXL FAMILY

Citation
Ke. Crosier et Ps. Crosier, NEW INSIGHTS INTO THE CONTROL OF CELL-GROWTH - THE ROLE OF THE AXL FAMILY, Pathology, 29(2), 1997, pp. 131-135
Citations number
43
Categorie Soggetti
Pathology
Journal title
ISSN journal
00313025
Volume
29
Issue
2
Year of publication
1997
Pages
131 - 135
Database
ISI
SICI code
0031-3025(1997)29:2<131:NIITCO>2.0.ZU;2-K
Abstract
Axl, Dtk and Mer are recently described receptors that constitute a ne w receptor tyrosine kinase subfamily. They bind the vitamin K-dependen t protein growth-arrest-specific gene 6 (Gas6) that is structurally re lated to the anticoagulation factor protein S. Studies suggest a role for these receptors in developmental processes, in the function of the hematopoietic and nervous systems and in tumorigenesis.