UTERINE MYOMAS AND FACTORS ASSOCIATED WITH HYSTERECTOMY IN PREMENOPAUSAL WOMEN

OBJECTIVE: Our purpose was to describe clinical characteristics in pre menopausal women with uterine myomas and to identify factors associate d with hysterectomy. STUDY DESIGN: Data were collected by chart abstra ction in 421 premenopausal women with myomas and analyzed by univariat e and multivariable regression. RESULTS: Over a median follow-up perio d of 29 months, 86% of women had symptoms associated with myomas and 4 0% had an increase in uterine size of >2 gestational weeks. By multiva riable regression, bleeding symptoms at presentation and previous surg ical history of cholecystectomy and adhesiolysis were significantly as sociated with greater odds of hysterectomy. There was a significant in teraction between age and uterine size, so that as age increased, uter ine size had a greater impact on the likelihood of hysterectomy. CONCL USIONS: In this cohort of premenopausal women myomas were associated w ith symptoms in almost all women over the follow-up period. Hysterecto my was performed in 22% of women overall.