Impact of flavophospholipol and vancomycin on conjugational transfer of vancomycin resistance plasmids

Citation
S. Riedl et al., Impact of flavophospholipol and vancomycin on conjugational transfer of vancomycin resistance plasmids, ANTIM AG CH, 44(11), 2000, pp. 3189-3192
Citations number
30
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
11
Year of publication
2000
Pages
3189 - 3192
Database
ISI
SICI code
0066-4804(200011)44:11<3189:IOFAVO>2.0.ZU;2-4
Abstract
The influence of vancomycin and flavophospholipol (FPL) on the transfer rat e of conjugative plasmids harboring the vancomycin resistance operon vanA w as determined in several clinical and animal isolates of Enterococcus faeci um. FPL significantly inhibited the frequency of transfer of conjugative Va nA plasmids up to 70-fold. Vancomycin had no significant effect on the tran sfer rate of VanA plasmids.