S. Riedl et al., Impact of flavophospholipol and vancomycin on conjugational transfer of vancomycin resistance plasmids, ANTIM AG CH, 44(11), 2000, pp. 3189-3192
The influence of vancomycin and flavophospholipol (FPL) on the transfer rat
e of conjugative plasmids harboring the vancomycin resistance operon vanA w
as determined in several clinical and animal isolates of Enterococcus faeci
um. FPL significantly inhibited the frequency of transfer of conjugative Va
nA plasmids up to 70-fold. Vancomycin had no significant effect on the tran
sfer rate of VanA plasmids.