Heterogeneity of AmpC cephalosporinases of Hafnia alvei clinical isolates expressing inducible or constitutive ceftazidime resistance phenotypes

Authors
Girlich, D Naas, T Bellais, S Poirel, L Karim, A Nordmann, P
Citation
D. Girlich et al., Heterogeneity of AmpC cephalosporinases of Hafnia alvei clinical isolates expressing inducible or constitutive ceftazidime resistance phenotypes, ANTIM AG CH, 44(11), 2000, pp. 3220-3223
Citations number
19
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
11
Year of publication
2000
Pages
3220 - 3223
Database
ISI
SICI code
0066-4804(200011)44:11<3220:HOACOH>2.0.ZU;2-L
Abstract
Ten unrelated Hafnia alvei clinical isolates were grouped according to eith er their low-level and inducible cephalosporinase production or their high- level and constitutive cephalosporinase production phenotype. Their AmpC se quences shared 85 to 100% amino acid identity. The immediate genetic enviro nment of ampC genes was conserved in H. alvei isolates but was different fr om that found in other ampC-possessing enterobacterial species.