Synthesis of heterocyclic quinones containing bridgehead nitrogen atom from 2-aminonaphtho[2,3-d]thiazole-4,9-dione

Authors
Citation
Rf. Fandy, Synthesis of heterocyclic quinones containing bridgehead nitrogen atom from 2-aminonaphtho[2,3-d]thiazole-4,9-dione, ARCH PH RES, 23(5), 2000, pp. 446-449
Citations number
14
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIVES OF PHARMACAL RESEARCH
ISSN journal
02536269 → ACNP
Volume
23
Issue
5
Year of publication
2000
Pages
446 - 449
Database
ISI
SICI code
0253-6269(200010)23:5<446:SOHQCB>2.0.ZU;2-F
Abstract
Imidazonaphthothiazole derivatives 3 similar to6 were prepared by treatment of 2-aminonaphtho[2,3-d]-thiazole-4,9-dione(1) with phenacyl bromide, chlo roacetic acid, diethyl oxalate and 2,3-dichloroquinoxaline respectively. Th e reaction of 1 with ethyl acrylate, ethyl acetoacetate and diethyl malonat e gave the corresponding naphthothiazolopyrimidine derivatives 8 similar to 11.