Synthesis and in vitro cytotoxicity of 2-alkylaminosubstituted quinoline derivatives

Authors
Lee, H Lee, J Hong, SS Yang, SI Jung, SH Jahng, Y Cho, JS
Citation
H. Lee et al., Synthesis and in vitro cytotoxicity of 2-alkylaminosubstituted quinoline derivatives, ARCH PH RES, 23(5), 2000, pp. 450-454
Citations number
7
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIVES OF PHARMACAL RESEARCH
ISSN journal
02536269 → ACNP
Volume
23
Issue
5
Year of publication
2000
Pages
450 - 454
Database
ISI
SICI code
0253-6269(200010)23:5<450:SAIVCO>2.0.ZU;2-5
Abstract
Eight 2-alkylaminosubstituted 5,8-dimethoxy-4-methylquinolines and nine 2-a lkylaminosubstituted or 2,6-disubstituted 4-methylquinoline-5,8-diones were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines (HOP62, SK-OV-3, HCT15 and SF295).