Rolandic encephalopathy and epilepsia partialis continua following bone marrow transplant

Epilepsia partialis continua (EPC) is a condition defined by prolonged foca l myoclonus, Often resistant to therapy, EPC in children is frequently pres ent in Rasmussen encephalitis, a form of chronic encephalitis of uncertain etiology, We discuss a child who developed bilateral EPC 5 months after a b one marrow transplant. Neuroimaging studies showed signal abnormalities on both sensory-motor areas. An extensive search failed to reveal the etiology of the disorder, but treatment with a broad-spectrum anti-viral agent was associated with resolution of the process. An unidentified infectious agent may be responsible for an encephalitis of the motor strip in immunosuppres sed patients.