M. Musso et al., Crohn's disease complicated by relapsed extranodal Hodgkin's lymphoma: prolonged complete remission after unmanipulated PBPC autotransplant, BONE MAR TR, 26(8), 2000, pp. 921-923
Citations number
17
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD
), which are thought to result from an inappropriate immunologic (autoimmun
e) response to luminal antibodies. Allogeneic stem cell transplantation (SC
T) performed for coincidental diseases is able to cure both leukaemia and C
rohn's disease, Autologous SCT is currently performed worldwide for severe
autoimmune diseases (SADs) because of its reduced transplant-related mortal
ity (TRM), We report the case of a 30-year-old male patient with a ill-year
history of severe Crohn's disease, who developed Hodgkin's disease and rec
eived an unmanipulated peripheral blood autologous transplant. Three years
after the transplant the patient is in complete treatment-free remission of
both diseases.