Crohn's disease complicated by relapsed extranodal Hodgkin's lymphoma: prolonged complete remission after unmanipulated PBPC autotransplant

Citation
M. Musso et al., Crohn's disease complicated by relapsed extranodal Hodgkin's lymphoma: prolonged complete remission after unmanipulated PBPC autotransplant, BONE MAR TR, 26(8), 2000, pp. 921-923
Citations number
17
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
26
Issue
8
Year of publication
2000
Pages
921 - 923
Database
ISI
SICI code
0268-3369(200010)26:8<921:CDCBRE>2.0.ZU;2-8
Abstract
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD ), which are thought to result from an inappropriate immunologic (autoimmun e) response to luminal antibodies. Allogeneic stem cell transplantation (SC T) performed for coincidental diseases is able to cure both leukaemia and C rohn's disease, Autologous SCT is currently performed worldwide for severe autoimmune diseases (SADs) because of its reduced transplant-related mortal ity (TRM), We report the case of a 30-year-old male patient with a ill-year history of severe Crohn's disease, who developed Hodgkin's disease and rec eived an unmanipulated peripheral blood autologous transplant. Three years after the transplant the patient is in complete treatment-free remission of both diseases.