Enantiopure arene dioxides: chemoenzymatic synthesis and application in the production of trans-3,4-dihydrodiols

Authors
Boyd, DR Sharma, ND O'Dowd, CR Hempenstall, F
Citation
Dr. Boyd et al., Enantiopure arene dioxides: chemoenzymatic synthesis and application in the production of trans-3,4-dihydrodiols, CHEM COMMUN, (21), 2000, pp. 2151-2152
Citations number
21
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
21
Year of publication
2000
Pages
2151 - 2152
Database
ISI
SICI code
1359-7345(2000):21<2151:EADCSA>2.0.ZU;2-L
Abstract
Enantiopure syn- and anti-arene dioxides are synthesised from cis-dihydrodi ol metabolites; anti-benzene dioxides are reduced to enantiopure trans-3,4- dihydrodiols while syn-benzene dioxides racemise thermally via 1,4-dioxocin s.