We report a case of persistent annular erythema of infancy in a 4-month-old
boy. Physical and laboratory parameters showed no sign of internal disease
or specific infection except a massive Candida albicans colonization (> 10
(3) organisms/mm(3)) of the lower gastrointestinal tract. Oral treatment wi
th amphotericin B for 2 weeks resulted in a complete remission of the skin
lesions indicating Candida colonization as a trigger.