M. Schierova et al., Sulfate assimilation in Aspergillus terreus: analysis of genes encoding ATP-sulfurylase and PAPS-reductase, CURR GENET, 38(3), 2000, pp. 126-131
Two genes for the sulfate assimilation pathway in Aspergillus terreus were
cloned. The genes sAT (coding for PAPS-reductase) and sCT(coding for ATP-su
lfurylase) form a small gene cluster. Both genes are similar to their homol
ogs in A. nidulans (sA and sC), Penicillium chrysogenum (nps) and Saccharom
yces cerevisiae (MET3 and MET16). In the coding sequence of the sCT gene, a
typical non-functional APS-kinase-like domain is present. The sCT gene is
expressed in A. nidulans, but its expression there is less sensitive to met
hionine level than in the original species. Two regions 5' upstream of sAT
were found to be similar to those of sA.