Antiretroviral therapy of HIV-1 infection: established treatment strategies and new therapeutic options

Authors
Kaufmann, GR Cooper, DA
Citation
Gr. Kaufmann et Da. Cooper, Antiretroviral therapy of HIV-1 infection: established treatment strategies and new therapeutic options, CURR OPIN M, 3(5), 2000, pp. 508-514
Citations number
63
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
CURRENT OPINION IN MICROBIOLOGY
ISSN journal
13695274 → ACNP
Volume
3
Issue
5
Year of publication
2000
Pages
508 - 514
Database
ISI
SICI code
1369-5274(200010)3:5<508:ATOHIE>2.0.ZU;2-1
Abstract
Recently, studies have shown that non-nucleoside reverse transcriptase inhi bitors, such as efavirenz or nevirapine, in combination with two nucleoside analogues have an antiretroviral potency comparable to protease inhibitor containing regimens. Triple combination therapy that includes a non-nucleos ide reverse transcriptase inhibitor can therefore be regarded as an effecti ve alternative first-line treatment of HIV-1 infection.