The relationship between psychopathology and smoking cessation treatment response

The study evaluated the relationship of psychopathology to treatment respon se of 208 smokers prescribed transdermal nicotine (8 weeks). Participants w ere relatively high functioning (DSM-IV axis V score) outpatients in a univ ersity-based clinic. The primary study objective was to determine whether p atients with a history of either a DSM-IV axis I or II diagnosis would have poorer during treatment response (patch adherence, smoking) and lower rate s of smoking cessation at post-patch follow-up (study weeks 9, 26, 52) than those without a diagnosis. While there was some indication that patients w ith a history of psychopathology wore the patch less Frequently, psychopath ology was not associated with during- and post-treatment smoking. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.