Major depressive and dysthymic disorders are recurrent and sometimes persis
tent unipolar mood disorders, which often present in childhood and adolesce
nce. Depressive episodes may increase in severity and duration with recurre
nce and are associated with substantial morbidity and risk of suicide. The
role of child and adolescent mental health services in early intervention a
nd management is thus of major importance. This paper draws together curren
t research evidence and common clinical practice, in guidelines for the spe
cialist management of depressive disorders in childhood and adolescence. Bo
th psychotherapy and pharmacotherapy have been found to be beneficial for t
he acute treatment of children and adolescents with depressive disorders. B
ased on current evidence, psychotherapy may be the first treatment for most
depressed youngsters, but antidepressants should be considered for those w
ith severe depression. All patients need continuation therapy, and some wil
l need maintenance treatment. Evidence supporting the efficacy of psycholog
ical and psychopharmacological treatments are reviewed. An integration of a
pproaches is suggested as a guideline for treatment planning.