O-[2-Hydroxy-3-(dialkylamino)propyl]ethers of (+)-1,7,7-trimethyl bicyclo[2.2.1]heptan-2-one oxime (camphor oxime) with analgesic and antiarrhythmic activities

Authors
Schenone, S Bruno, O Ranise, A Bondavalli, F Filippelli, W Falcone, G Rinaldi, B
Citation
S. Schenone et al., O-[2-Hydroxy-3-(dialkylamino)propyl]ethers of (+)-1,7,7-trimethyl bicyclo[2.2.1]heptan-2-one oxime (camphor oxime) with analgesic and antiarrhythmic activities, FARMACO, 55(6-7), 2000, pp. 495-498
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
FARMACO
ISSN journal
0014827X → ACNP
Volume
55
Issue
6-7
Year of publication
2000
Pages
495 - 498
Database
ISI
SICI code
0014-827X(200006/07)55:6-7<495:OO(B>2.0.ZU;2-A
Abstract
A novel series of O-[2-hydroxy-3-(dialkylamino)propyl]ethers of (+)-camphor oxime was prepared and tested for its cardiovascular, analgesic and anti-i nflammatory properties. No significant anti-inflammatory and hypotensive ac tivities were displayed by any of the compounds, whereas several of them ar e reasonably active as antiarrhythmic and analgesic agents. (C) 2000 Elsevi er Science S.A. All rights reserved.