In the 1,3-dipolar cycloaddition of aliphatic nitrile to selected olefins,
a series of 4,5-dihydroisoxazoles substituted with various functional group
s, ester, carbonyl and ethereal, was obtained. These compounds were investi
gated for antimicrobial activity on chosen strains. (C) 2000 Elsevier Scien
ce S.A. All rights reserved.