Monitoring of minimal residual disease and mixed chimerism in a case of high-risk TEL/AML1-positive acute lymphocytic leukemia

Authors
Sedlacek, P Trka, J Zuna, J Hrusak, O Honzatkova-Krskova, L Stary, J
Citation
P. Sedlacek et al., Monitoring of minimal residual disease and mixed chimerism in a case of high-risk TEL/AML1-positive acute lymphocytic leukemia, HAEMATOLOG, 85(10), 2000, pp. 1100-1102
Citations number
8
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
10
Year of publication
2000
Pages
1100 - 1102
Database
ISI
SICI code
0390-6078(200010)85:10<1100:MOMRDA>2.0.ZU;2-H
Abstract
We report the case of a child with acute lymphocytic leukemia with a combin ation of positive (TEL/AML1 positivity, age, low level minimal residual dis ease before bone marrow transplantation) and negative (poor prednisone resp onse, high leukocytosis) prognostic features. We used molecular-genetic tec hniques and flow cytometry for the follow-up of minimal residual disease.