Use of molecular techniques to confirm true re-emergence of an original clone and to track minimal residual disease in acute lymphoblastic leukemia

Authors
Valetto, A Anselmi, G Scuderi, F Lanciotti, M Chiesa, V Dini, G
Citation
A. Valetto et al., Use of molecular techniques to confirm true re-emergence of an original clone and to track minimal residual disease in acute lymphoblastic leukemia, HAEMATOLOG, 85(10), 2000, pp. 1102-1103
Citations number
10
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
10
Year of publication
2000
Pages
1102 - 1103
Database
ISI
SICI code
0390-6078(200010)85:10<1102:UOMTTC>2.0.ZU;2-G
Abstract
We report the case of a young girl whose acute lymphoblastic leukemia (ALL) recurred as lymphoblastic lymphoma 6.6 years after diagnosis. Analysis of minimal residual disease (MRD) allowed tracking of the leukemic clone durin g the phases of therapy, confirming that relapse was a true re-emergence of the original clone.