Expansion of CD3(+)CD56(+) cytotoxic cells from patients with chronic lymphocytic leukemia: in vitro efficacy

Authors
Lefterova, P Schakowski, F Buttgereit, P Scheffold, C Huhn, D Schmidt-Wolf, IGH
Citation
P. Lefterova et al., Expansion of CD3(+)CD56(+) cytotoxic cells from patients with chronic lymphocytic leukemia: in vitro efficacy, HAEMATOLOG, 85(10), 2000, pp. 1108-1109
Citations number
7
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
10
Year of publication
2000
Pages
1108 - 1109
Database
ISI
SICI code
0390-6078(200010)85:10<1108:EOCCCF>2.0.ZU;2-L
Abstract
Cytokine-induced killer cells were expanded from 12 patients with chronic l ymphatic leukemia. In these cultures, T-cells increased significantly from less than 10% to 56.3+/- 29.4% after 14 days. Similarly, the percentage of cells expressing the natural killer-cell marker CD56 increased significantl y to 31.8+/-26.3%.