A convenient one pot synthesis of pyrido[2,3-d]-pyrimidines and pyrimido[2,3-c]pyrimidines (N-5-deazapetrins)

Authors
Mekheimer, RA Abd El-Nabi, HA Abd-Elhameed, AM Sadek, KU
Citation
Ra. Mekheimer et al., A convenient one pot synthesis of pyrido[2,3-d]-pyrimidines and pyrimido[2,3-c]pyrimidines (N-5-deazapetrins), HETEROCYC C, 6(4), 2000, pp. 301-307
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLIC COMMUNICATIONS
ISSN journal
07930283 → ACNP
Volume
6
Issue
4
Year of publication
2000
Pages
301 - 307
Database
ISI
SICI code
0793-0283(2000)6:4<301:ACOPSO>2.0.ZU;2-1
Abstract
A convenient one pot synthesis of pyrido[2,3-d]pyrimidines and pyrimido[2,3 -c]pyrimidines via reaction of 6-amino-2-oxo-4-thioxotetrahydropyrimidine 1 with cinnamonitrile derivatives 2 has been reported.