CONTINUOUS IGG PRODUCTION BY MYELOMA CELLS IMMOBILIZED WITHIN POROUS SUPPORT PARTICLES

Authors
YAMAJI H FUKUDA H
Citation
H. Yamaji et H. Fukuda, CONTINUOUS IGG PRODUCTION BY MYELOMA CELLS IMMOBILIZED WITHIN POROUS SUPPORT PARTICLES, Journal of fermentation and bioengineering, 83(5), 1997, pp. 489-491
Citations number
7
Categorie Soggetti
Food Science & Tenology","Biothechnology & Applied Migrobiology
Journal title
Journal of fermentation and bioengineering → ACNP
ISSN journal
0922338X
Volume
83
Issue
5
Year of publication
1997
Pages
489 - 491
Database
ISI
SICI code
0922-338X(1997)83:5<489:CIPBMC>2.0.ZU;2-M
Abstract
IgG production kinetics of mouse myeloma MPC-11 cells immobilized with in porous polyvinyl formal resin biomass support particles (BSPs) was evaluated by monitoring of lactate dehydrogenase activities and IgG co ncentration in a perfusion culture of the cells. Cells immobilized wit hin the BSPs could stably maintain a high specific IgG production rate , comparable to the maximum production rate in a static culture of non -immobilized MPC-11 cells, over a long period.