Microwave-induced fast synthesis and optical resolution of 9H-carbazole-2-carboxylic acids enantiomers

Authors
Lao, WJ Yu, ZW Liu, YQ Ou, QY
Citation
Wj. Lao et al., Microwave-induced fast synthesis and optical resolution of 9H-carbazole-2-carboxylic acids enantiomers, J PRAK CHEM, 342(6), 2000, pp. 596-598
Citations number
24
Categorie Soggetti
Chemistry
Journal title
JOURNAL FUR PRAKTISCHE CHEMIE-PRACTICAL APPLICATIONS AND APPLIED CHEMISTRY
ISSN journal
14369966 → ACNP
Volume
342
Issue
6
Year of publication
2000
Pages
596 - 598
Database
ISI
SICI code
1436-9966(2000)342:6<596:MFSAOR>2.0.ZU;2-L
Abstract
Fast synthesis of a series 9H-carabzole-2-carboxylic acids enantiomers 9-13 by N-alkylation reaction of the carbazole and bromo ester under microwave irradiation is described using DMF as solvent. The HPLC optical resolution of these enantiomers were performed on amylose tris(phenylcarbamate)-coated aminopropylated silica gel (ATPC) column.