A new entry for short and regioselective synthesis of [1,2,4]Triazolo[4,3-b][1,2,4]-triazin-7(1H)-ones

Authors
Shawali, AS Gomha, SM
Citation
As. Shawali et Sm. Gomha, A new entry for short and regioselective synthesis of [1,2,4]Triazolo[4,3-b][1,2,4]-triazin-7(1H)-ones, J PRAK CHEM, 342(6), 2000, pp. 599-604
Citations number
26
Categorie Soggetti
Chemistry
Journal title
JOURNAL FUR PRAKTISCHE CHEMIE-PRACTICAL APPLICATIONS AND APPLIED CHEMISTRY
ISSN journal
14369966 → ACNP
Volume
342
Issue
6
Year of publication
2000
Pages
599 - 604
Database
ISI
SICI code
1436-9966(2000)342:6<599:ANEFSA>2.0.ZU;2-F
Abstract
Reaction of benzenediazonium chloride with active [1,2,4]triazin-3-ylthio-m ethylene compounds 3 afforded the azo coupling products 5, which yielded [1 ,2,4]triazolo[4,3-b][1,2,4]triazin-7(1H)-ones 8 upon treatment with sodium ethoxide in ethanol. The latter products 8 were characterized on the basis of alternate synthesis and spectral data. The mechanism of formation of 8 a nd the regiochemistry of the studied reactions are discussed.