Plants have evolved complex mechanisms to defend themselves against pa
thogens, and thus a great deal of attention has been directed towards
elucidating the molecular nature of resistance. Salicylic acid has bee
n shown to be a signaling molecule involved in both local defense reac
tions at infection sites and the induction of systemic resistance. Alt
hough it is still unclear whether this compound can serve as a long-di
stance messenger signaling the presence of a pathogen, its synthesis a
nd accumulation are important requirements for defense responses, Rece
nt advances have further established the key role of the signal transd
uction pathways dependent on salicylic acid.