THE GENETICS OF OBESITY

Authors
NAGGERT J HARRIS T NORTH M
Citation
J. Naggert et al., THE GENETICS OF OBESITY, Current opinion in genetics & development, 7(3), 1997, pp. 398-404
Citations number
60
Categorie Soggetti
Biology,"Cell Biology","Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
Current opinion in genetics & development → ACNP
ISSN journal
0959437X
Volume
7
Issue
3
Year of publication
1997
Pages
398 - 404
Database
ISI
SICI code
0959-437X(1997)7:3<398:TGOO>2.0.ZU;2-I
Abstract
Despite the influence of obesity in predisposing to many diseases, and evidence for high heritability, efforts to identify human genes with major effects on bodyweight have not yet been successful. In contrast, remarkable progress has been made in the identification and character ization of the genes mutated in five monogenic mouse models of obesity . These genes have led to new insights into the etiology of obesity an d provide promising targets for therapeutic intervention.