This note describes an improvement to an accurate, robust, and fast re
gistration algorithm (Alexander, M.E. and Somorjai, R.L., Mag. Reson.
Imaging, 14:453-468, 1996). A computationally inexpensive preregistrat
ion method is proposed, consisting df simply aligning the image centro
ids, from which estimates of the translation shifts are derived. The m
ethod has low sensitivity to noise, and provides starting values of su
fficient accuracy for the iterative registration algorithm to allow ac
curate registration of images that have significant levels of noise an
d/or large misalignments. Also, it requires a smaller computational ef
fort than the Fourier Phase Matching (FPM) preregistration method used
previously. The FPM method provides accurate preregistration for low-
noise images, but fails when significant noise is present. For testing
the various methods, a 256 x 256 pixel T-2()-weighted image was tran
slated, rotated, and scaled to produce large misalignments and occlusi
on at the image boundaries. The two situations of no noise being prese
nt in the images and in which Gaussian noise is added, were tested. Af
ter preregistration, the images were registered by applying one or sev
eral passes of the iterative algorithm at different levels of preblurr
ing of the input images. Results of using the old and new preregistrat
ion methods, as well as no preregistration, are compared for the final
accuracy of recovery of registration parameters. In addition, the per
formances of three robust estimators: Least Median of Squares, Least T
rimmed Squares, and Least Winsorized Mean, are compared with those of
the nonrobust Least Squares and Woods' methods, and found to converge
to correct solutions in cases where the nonrobust methods do not. (C)
1997 Elsevier Science Inc.