In previous studies of the relation between mitral annulus motion (MAM) and
left ventricular election fraction (EF), a linear relationship has been su
ggested. In this meta-analysis of 434 patients, we show that the relation i
s nonlinear and that a linear regression model overestimates EP in the lowe
r range of MAM. The relation is better described by an S function and is in
fluenced by age and heart size.