Developmental expression of the estrogen receptor-related receptor gamma in the nervous system during mouse embryogenesis

The ERR's (estrogen receptor-related receptors) are constitutive activators of the classical estrogen response element. In this report, we demonstrate that ERR gamma is highly expressed in the nervous system of the developing mouse embryo and that the adult pattern of expression of ERR gamma is, wit h few exceptions, established during embryogenesis. Transcripts are prefere ntially detected in already differentiating areas of the nervous system. (C ) 2000 Elsevier Science Ireland Ltd. All rights reserved.