E2F transcription factors are differentially expressed in murine gametes and early embryos

Authors
Palena, A Mangiacasale, R Magnano, AR Barberi, L Giordano, R Spadafora, C Lavia, P
Citation
A. Palena et al., E2F transcription factors are differentially expressed in murine gametes and early embryos, MECH DEVEL, 97(1-2), 2000, pp. 211-215
Citations number
10
Categorie Soggetti
Cell & Developmental Biology
Journal title
MECHANISMS OF DEVELOPMENT
ISSN journal
09254773 → ACNP
Volume
97
Issue
1-2
Year of publication
2000
Pages
211 - 215
Database
ISI
SICI code
0925-4773(200010)97:1-2<211:ETFADE>2.0.ZU;2-U
Abstract
We have examined the murine genes encoding transcription factors E2F1, -3, -5 and -6 in gametes and early embryos. All genes are expressed as maternal transcripts and all are efficiently transcribed after the blastocyst stage . Between those two stages, each E2F mRNA is transcribed with a distinctive and unique pattern. E2F proteins are also differentially expressed and com partmentalized in pre-implantation embryos. (C) 2000 Elsevier Science Irela nd Ltd. All rights reserved.