Do infectious diseases drive MHC diversity?

Authors
Jeffery, KJM Bangham, CRM
Citation
Kjm. Jeffery et Crm. Bangham, Do infectious diseases drive MHC diversity?, MICROBES IN, 2(11), 2000, pp. 1335-1341
Citations number
64
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
2
Issue
11
Year of publication
2000
Pages
1335 - 1341
Database
ISI
SICI code
1286-4579(200009)2:11<1335:DIDDMD>2.0.ZU;2-F
Abstract
The primary function of the major histocompatibility complex (MHC) is to al low the immune system to identify infectious pathogens and eliminate them. Infectious diseases are now thought to be the main selection force that dri ves and maintains the extraordinary diversity of the MHC. (C) 2000 Editions scientifiques et medicales Elsevier SAS.