A. Mulenga et al., Issues in tick vaccine development: identification and characterization ofpotential candidate vaccine antigens, MICROBES IN, 2(11), 2000, pp. 1353-1361
It is well established that acquired immunity against tick infestation can
be induced by repeated tick infestation or by active immunization with eith
er crude or purified native as well as recombinant antigens. This review pr
ovides insights into the development of tick vaccines with reference to ide
ntification, purification and molecular cloning of candidate target antigen
s. (C) 2000 Editions scientifiques et medicales Elsevier SAS.