The purpose of this investigation was to describe the relationship between
the central activation ratio (CAR) and the percent maximum voluntary effort
(% MVE) during isometric quadriceps femoris contractions. Twenty-one healt
hy, young adults participated in three test sessions. During each session.
one of three train types was tested: a 100-Hz 120-ms train, a 100-Hz 250-ms
train, or a 50-Hz 500-ms train. Subjects were seated on a force dynamomete
r and stabilized to perform a 3-5-s isometric knee extension at MVE. Force
targets were set at 25, 50, 75, and 100% of the MVE. With 5 min rest betwee
n efforts, subjects produced forces at the specified target levels. When ea
ch target was reached, the test train was delivered to quantify the amount
of central activation. There were no significant differences in CARs across
train types during maximal efforts, but during submaximal efforts at 25 an
d 50%, the 100-Hz 250-ms and 50-Hz 500-ms trains produced significantly low
er CARs than the 100-Hz 120-ms train. The relationship between the CAR and
the %MVE was curvilinear and best described by a second-order polynomial fo
r all three train types. If tests of central activation are going to be use
d clinically, it is important to know the relationship between the CAR and
voluntary effort; however, further study will be required to extend these r
esults to specific patient populations. (C) 2000 John Wiley & Sons, Inc.