Prostatic malakoplakia: three cases

Malakoplakia is a granulomatous inflammatory disorder occuring rarely in th e prostate. We report our experience with three patients aged from 54 to 75 years old. Clinical presentations were unspecific. All patients presented with a past history of urinary tract infection. Ul trasound study revealed hypoechoic peripheral zone lesions. Histological examination showed a diffu se granulomatous inflammation with numerous histiocytes containing Michaeli s-Gutmann bodies. In the prostate, malakoplakia is a histological variant o f granulomatous chronic prostatitis following urinary infections. Clinically and radiologically, the differential diagnosis with adenocarcino ma is difficult. The symptoms disappear with a prolongated antibiotic treat ment.