In recent years, doubts have been cast on the validity of the conventionall
y applied peak-to-peak method for dose estimation. Alternative methods are
reviewed, including dose versus magnetic field plots, deconvolution using G
aussian and Lorentzian line shapes, and fitting the absorption and derivati
ve spectra with an experimentally derived spectrum of the CO2- radical. The
latter methods most probably yield the most reliable results. Conventional
peak-to-peak dose estimations are closely similar. On a 2-sigma basis, nea
rly all methods yield statistically indistinguishable results. (C) 2000 Els
evier Science Ltd. All rights reserved.