A. Momose et al., Blood vessels: Depiction at phase-contrast X-ray imaging without contrast agents in the mouse and rat - Feasibility study, RADIOLOGY, 217(2), 2000, pp. 593-596
Citations number
14
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
The ability of phase-contrast x-ray imaging to depict blood vessels with; o
ut contrast agents was tested by observing livers of a mouse and a rat with
synchrotron x rays, Livers were excised by tying arteries and veins to pre
vent blood from flowing out of the liver. An x-ray interferometer was used
to obtain x-ray phase contrast. With the technique of phase-shifting x-ray
interferometry, the image mapping x-ray phase shift caused by a liver was m
easured. The x-ray phase shift caused by blood was substantially different
from that caused by other soft tissues; consequently, trees of blood vessel
s were revealed on the image. Vessels with diameter smaller than 0.1 mm wer
e recognized. This result allows new possibilities for investigation of the
vascular system.